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KMID : 0857020060210010318
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Kosin Medical Journal
2006 Volume.21 No. 1 p.318 ~ p.322
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Effects of Eucalyptus and Geranium on Tumor Cell Growth
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Kim Kwang-Hyuk
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Abstract
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Background : Aromatherpy is the controlled use of essential oils to promote health and well-being. The most frequent form of using the essential oils is through massage; however, essential oil can be used in a variety of other ways such as inhalation, vaporization, in the bath and through a compress.
Methods : In this work we have investigated the effect of eucalyptus and geranium on the anti-proliferative activities for tumor cell lines.
Results : The direct cytotoxicity of essential oils or essential oil-combined chemotherapeutic agents fro tumor cells, K562 was observed. At certain doses (eucalyptus; 10, 100 ㎍) of the essential oils, K562 cells were increased in comparison with the control group. The cell growth of geranium-combined 5-FU groups was lower than of 5-FU single group. But the cell proliferation of essential oil-combined groups was higher than that of antitumor agent single group at the certain doses (mitomycin C or 5-Fu + eucalyptus, mitomicin C+ Geranium).
Conclusions : These kinds of essential oils showed the usefulness in cancer patients may demand some deliberations.
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KEYWORD
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Eucalyptus, Geraniumm, Mitomycin C, 5-FU, Cytotoxicity, Tumor cell
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